Impact of Evolving Evidence on Pharmacological Therapy for Alcohol‐Associated Hepatitis in Alberta: A Population‐Based Study of Practice Trends and <scp>MELD</scp> ‐Stratified Effectiveness of Corticosteroids
RCT evidence led to a rapid reversal in PTX prescribing prior to formal guideline updates. Real-world data support a modest short-term benefit of CS and illustrate the potential of target trial emulation to assess treatment effectiveness in specific groups of patients.
Authors
- J. G. Abraldes
- Abdel‐Aziz Shaheen
- Bryce Tkachuk
- Meng Wang
Institutions
- Alberta Health Services (CA)
- University of Alberta (CA)
- University of Calgary (CA)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1111/apt.70517
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research