Efficacy and safety of preservative-free versus preserved timolol eye drops in glaucoma: A randomized crossover study

PF-timolol eye drops achieved a greater IOP reduction at week 6 but showed comparable efficacy to P-timolol by week 12, while providing additional advantages in ocular safety outcomes and subjective tolerability. PF-timolol offers an effective and safer option for glaucoma management, particularly in patients sensitive to preservatives.

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Publication Details

Journal
Journal of the Chinese Medical Association
Published
2026-01-08
DOI
https://doi.org/10.1097/jcma.0000000000001338
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of preservative-free versus preserved timolol eye drops in glaucoma: A randomized crossover study

Tung-Mei Kuang, Y Y Ko, Yu‐Chieh Ko, M. S. Chen et al.
Journal of the Chinese Medical Association
Glaucoma and retinal disorders
article

Efficacy and safety of preservative-free versus preserved timolol eye drops in glaucoma: A randomized crossover study

Tung-Mei Kuang, Y Y Ko, Yu‐Chieh Ko, M. S. Chen, Catherine Jui-Ling Liu, Yu-Fan Chang, Chia-Chi Fan
article en

Abstract

PF-timolol eye drops achieved a greater IOP reduction at week 6 but showed comparable efficacy to P-timolol by week 12, while providing additional advantages in ocular safety outcomes and subjective tolerability. PF-timolol offers an effective and safer option for glaucoma management, particularly in patients sensitive to preservatives.

Journal of the Chinese Medical AssociationVol. 89(2)
National Yang Ming Chiao Tung University (TW), University of Kang Ning (TW), Taipei Veterans General Hospital (TW), National Taiwan University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 95%
Glaucoma and retinal disorders
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