Pharmacodynamic individualization of phage therapy against a KPC-5-producing <i>Pseudomonas aeruginosa</i>

This highlights the potential of reverse translational pharmacokinetic/pharmacodynamic-driven approaches to guide rational phage selection strategies against individual clinical isolates while identifying potential antagonistic phage-phage interactions.

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Publication Details

Journal
JAC-Antimicrobial Resistance
Published
2025-12-19
DOI
https://doi.org/10.1093/jacamr/dlaf257
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacodynamic individualization of phage therapy against a KPC-5-producing Pseudomonas aeruginosa

Chen Liang, Brian M. Ho, Thomas D. Nguyen, Nicholas M. Smith et al.
JAC-Antimicrobial Resistance
Bacteriophages and microbial interactions
article

Pharmacodynamic individualization of phage therapy against a KPC-5-producing Pseudomonas aeruginosa

Chen Liang, Brian M. Ho, Thomas D. Nguyen, Nicholas M. Smith, Dwayne R. Roach, Tiffany Luong, Jacob T. Sanborn, Wood Troy
article en

Abstract

This highlights the potential of reverse translational pharmacokinetic/pharmacodynamic-driven approaches to guide rational phage selection strategies against individual clinical isolates while identifying potential antagonistic phage-phage interactions.

JAC-Antimicrobial ResistanceVol. 8(1)
San Diego State University (US), University at Buffalo, State University of New York (US)
Openalex Percentile: Top 27%
Bacteriophages and microbial interactions
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