Association of genetic predisposition to dyslipidemia and physical activity with incident dementia
Genetic predisposition to higher low-density lipoprotein cholesterol and lower high-density lipoprotein cholesterol is linked to increased dementia risk. Being physically active is associated with lower dementia risk across genetic risk profiles. Being physically active shows the strongest association with lower risk of vascular dementia.
Authors
- Ting Yang (ORCID: https://orcid.org/0000-0002-7027-5179)
- Lan Ding
- Yumei Liang
- Siqi Xie
- Dandan Sheng
- Jianping Jia
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Capital Medical University (CN)
- Beijing Geriatric Hospital (CN)
- Chinese Institute for Brain Research (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1002/alz.71079
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Scientific Instrument and Equipment Development Projects of China