Safety and tolerability of a standardized treatment regimen for Mycobacterium abscessus otomastoiditis
The multidrug treatment for M. abscessus otomastoiditis is frequently complicated by adverse events. Management by a specialized team is recommended. Frequent clinical monitoring, regular blood tests, audiograms and ECGs are recommended. Prophylactic antiemetics should be administered due to the high frequency of nausea and vomiting, particularly with tigecycline.
Authors
- Koen van Aerde (ORCID: https://orcid.org/0000-0003-3315-6282)
- Jakko van Ingen (ORCID: https://orcid.org/0000-0002-0581-2003)
- Stijn Bekkers (ORCID: https://orcid.org/0000-0002-8330-9243)
- Theresa Y.S. Leow (ORCID: https://orcid.org/0000-0002-8217-9424)
- Jérôme J. Waterval (ORCID: https://orcid.org/0000-0002-3424-6821)
- Henricus P. M. Kunst (ORCID: https://orcid.org/0000-0003-1162-6394)
- Arno Janssen
- Stefanie Henriet
- Sjoert A.H. Pegge
- Thijs.T.G. Jansen
- Myrthe K.S. Hol
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
Publication Details
- Journal
- International Journal of Pediatric Otorhinolaryngology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1016/j.ijporl.2026.112715
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00