Copy-Number Profiling and Methylation-Based Tumor Typing during Prenatal Cell-Free DNA Screening
Methylome and aneuploidy-aware cfDNA screening could substantially improve the diagnostic processes, pinpoint the origins of aneuploidy and improve cancer management during pregnancy.
Authors
- Antoine Passemiers (ORCID: https://orcid.org/0000-0002-9492-7311)
- Maarten Naesens (ORCID: https://orcid.org/0000-0002-5625-0792)
- Stefania Tuveri (ORCID: https://orcid.org/0000-0003-4051-4295)
- Leen Vancoillie
- Angelica Pagliazzi (ORCID: https://orcid.org/0000-0002-9128-6264)
- Tatjana Jatsenko (ORCID: https://orcid.org/0000-0002-7423-0963)
- Charlotte L. LeJeune (ORCID: https://orcid.org/0000-0002-8508-6995)
- Joris Robert Vermeesch (ORCID: https://orcid.org/0000-0002-3071-1191)
- F. Amant
- Liesbeth Lenaerts (ORCID: https://orcid.org/0000-0003-3565-2319)
- Peter Vandenberghe (ORCID: https://orcid.org/0000-0003-4719-1935)
- Nathalie Brison
- Kris Van Den Bogaert (ORCID: https://orcid.org/0000-0003-4525-5907)
- Dhanya Sudhakaran
- Ilse Parijs
- Qiang Fu
- Kristel Van Calsteren
Institutions
- The European Academy of Gynaecological Surgery (BE)
- Center for Human Genetics (US)
- Oncode Institute (NL)
- Centrum voor Gynaecologische Oncologie Amsterdam (NL)
- KU Leuven (BE)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1093/clinchem/hvaf167
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00