Astragalus polysaccharide improves canine sperm quality after chilled storage via promoting AMPK phosphorylation

The supplementation of APS to the extender protects canine sperm after chilled storage via promoting AMPK phosphorylation for enhancing the antioxidant capacity of sperm. These findings provide novel insight into the mechanism of APS in protecting canine sperm after chilled storage, and reveal the feasibility of APS supplementation to sperm extender for canine sperm preservation.

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Publication Details

Journal
BMC Veterinary Research
Published
2026-01-08
DOI
https://doi.org/10.1186/s12917-025-05254-1
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Astragalus polysaccharide improves canine sperm quality after chilled storage via promoting AMPK phosphorylation

Miaorong Huang, Ronggen Wang, Hengxi Wei, MinHua Hu et al.
BMC Veterinary Research
Sperm and Testicular Function
article

Astragalus polysaccharide improves canine sperm quality after chilled storage via promoting AMPK phosphorylation

Miaorong Huang, Ronggen Wang, Hengxi Wei, MinHua Hu, Shouquan Zhang, Ruiyan Liu, Xiaogang Huang, Zhihong Zhao, Li Li
article en

Abstract

The supplementation of APS to the extender protects canine sperm after chilled storage via promoting AMPK phosphorylation for enhancing the antioxidant capacity of sperm. These findings provide novel insight into the mechanism of APS in protecting canine sperm after chilled storage, and reveal the feasibility of APS supplementation to sperm extender for canine sperm preservation.

BMC Veterinary ResearchVol. 22(1)
South China Agricultural University (CN), China Resources (China) (CN), Poultry Research Institute (CN), Guangzhou Mechanical Engineering Research Institute (China) (CN)
Openalex Percentile: Top 96%
Sperm and Testicular Function
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