Transarterial embolization in osteoarthritis of the knee: Mechanism of action and current results

Before-and-after studies showed safe pain relief by GAE, but these findings have not been confirmed by the RCTs that have been carried out to date. Current evidence is mixed. Larger-scale, methodologically robust RCTs are needed so that the efficacy of GAE and its role in the treatment of symptomatic knee osteoarthritis can be reliably evaluated.

Authors

Federico Collettini (ORCID: https://orcid.org/0000-0001-5378-461X)
Tobias Winkler (ORCID: https://orcid.org/0000-0003-0727-4680)
Carsten Perka (ORCID: https://orcid.org/0000-0002-0993-581X)
Florian Nima Fleckenstein (ORCID: https://orcid.org/0000-0003-1088-1721)
Bernhard Gebauer
Dieter C Wirtz

Publication Details

Journal: Deutsches Ärzteblatt international
Published: 2026-02-13
DOI: https://doi.org/10.3238/arztebl.m2025.0221
Primary Topic: Osteoarthritis Treatment and Mechanisms
Type: article
Field-Weighted Citation Impact: 0.00

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article

Transarterial embolization in osteoarthritis of the knee: Mechanism of action and current results

Federico Collettini, Tobias Winkler, Carsten Perka, Florian Nima Fleckenstein et al.

Feb 13, 2026

Deutsches Ärzteblatt international

Osteoarthritis Treatment and Mechanisms

article

Transarterial embolization in osteoarthritis of the knee: Mechanism of action and current results

Federico Collettini, Tobias Winkler, Carsten Perka, Florian Nima Fleckenstein, Bernhard Gebauer, Dieter C Wirtz

February 13, 2026article en

Abstract

Before-and-after studies showed safe pain relief by GAE, but these findings have not been confirmed by the RCTs that have been carried out to date. Current evidence is mixed. Larger-scale, methodologically robust RCTs are needed so that the efficacy of GAE and its role in the treatment of symptomatic knee osteoarthritis can be reliably evaluated.

Deutsches Ärzteblatt international(Forthcoming)

Good health and well-being

Openalex Percentile: Top 96%

Osteoarthritis Treatment and Mechanisms

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