Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant <i>Klebsiella pneumoniae</i> (CRKP) Infections

High-risk genotypes of CRKP-defined in this study as KPC and OXA-48-like due to their strong association with increased transmission, drug resistance, and mortality-are associated with significantly increased mortality risk in infected patients, especially in China. These findings support risk stratification and personalized management of high-risk patients and provide evidence for regional prevention and control strategies. Further multicenter and mechanistic studies are warranted to improve clinical management and patient outcomes.

Authors

Institutions

Publication Details

Journal
Canadian Journal of Infectious Diseases and Medical Microbiology
Published
2026-01-01
DOI
https://doi.org/10.1155/cjid/1529426
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant Klebsiella pneumoniae (CRKP) Infections

Jiaojiao Xu, Ze Fang, Hailing Zeng, Qiongfang Zhang et al.
Canadian Journal of Infectious Diseases and Medical Microbiology
Antibiotic Resistance in Bacteria
article

Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant Klebsiella pneumoniae (CRKP) Infections

Jiaojiao Xu, Ze Fang, Hailing Zeng, Qiongfang Zhang, Bo Fang
article en

Abstract

High-risk genotypes of CRKP-defined in this study as KPC and OXA-48-like due to their strong association with increased transmission, drug resistance, and mortality-are associated with significantly increased mortality risk in infected patients, especially in China. These findings support risk stratification and personalized management of high-risk patients and provide evidence for regional prevention and control strategies. Further multicenter and mechanistic studies are warranted to improve clinical management and patient outcomes.

Canadian Journal of Infectious Diseases and Medical MicrobiologyVol. 2026(1)
Zhongshan People's Hospital (CN), Qujiang People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 96%
Antibiotic Resistance in Bacteria
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant <i>Klebsiella pneumoniae</i> (CRKP) Infections — Jiaojiao Xu, Ze Fang, et al. · Canadian Journal of Infectious Diseases and Medical Microbiology (2026) | TGRS Research Map | TGRS