Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant <i>Klebsiella pneumoniae</i> (CRKP) Infections
High-risk genotypes of CRKP-defined in this study as KPC and OXA-48-like due to their strong association with increased transmission, drug resistance, and mortality-are associated with significantly increased mortality risk in infected patients, especially in China. These findings support risk stratification and personalized management of high-risk patients and provide evidence for regional prevention and control strategies. Further multicenter and mechanistic studies are warranted to improve clinical management and patient outcomes.
Authors
- Jiaojiao Xu (ORCID: https://orcid.org/0000-0002-0828-3282)
- Ze Fang (ORCID: https://orcid.org/0009-0007-1438-6441)
- Hailing Zeng
- Qiongfang Zhang
- Bo Fang
Institutions
- Zhongshan People's Hospital (CN)
- Qujiang People's Hospital (CN)
Publication Details
- Journal
- Canadian Journal of Infectious Diseases and Medical Microbiology
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1155/cjid/1529426
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00