Efficacy of probiotic and synbiotic supplementation on the length of hospital stays and risk of postoperative mortality in patients undergoing surgery: an umbrella review of systematic reviews and meta-analyses of randomized clinical trials

The current review supports the efficacy of synbiotic and probiotic supplementation on decreasing the length of hospital stay in patients undergoing surgery. However, it is important to note that 42.3% of included systematic reviews and meta-analyses (SRMAs) were rated as 'critically low' quality using the AMSTAR2 tool, which necessitates cautious interpretation of findings.

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Publication Details

Journal
European journal of medical research
Published
2026-01-08
DOI
https://doi.org/10.1186/s40001-025-03756-0
Primary Topic
Probiotics and Fermented Foods
Type
article
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article

Efficacy of probiotic and synbiotic supplementation on the length of hospital stays and risk of postoperative mortality in patients undergoing surgery: an umbrella review of systematic reviews and meta-analyses of randomized clinical trials

Farhang Hameed Awlqadr, Sajjad Moradi, Behzad Ebrahimi, Mohammad Ali Hojjati Kermani et al.
European journal of medical research
Probiotics and Fermented Foods
article

Efficacy of probiotic and synbiotic supplementation on the length of hospital stays and risk of postoperative mortality in patients undergoing surgery: an umbrella review of systematic reviews and meta-analyses of randomized clinical trials

Farhang Hameed Awlqadr, Sajjad Moradi, Behzad Ebrahimi, Mohammad Ali Hojjati Kermani, Felicity MacIsaac, Sanaz Mehrabani, Kimia Mazinani, Seyed Mojtaba Ghoreishy, Faramarz Jalili
article en

Abstract

The current review supports the efficacy of synbiotic and probiotic supplementation on decreasing the length of hospital stay in patients undergoing surgery. However, it is important to note that 42.3% of included systematic reviews and meta-analyses (SRMAs) were rated as 'critically low' quality using the AMSTAR2 tool, which necessitates cautious interpretation of findings.

European journal of medical researchVol. 31(1)
Isfahan University of Medical Sciences (IR), Dalhousie University (CA), University of Maragheh (IR), Iran University of Medical Sciences (IR), Masih Daneshvari Hospital (IR), Sulaimani Polytechnic University (IQ), Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 95%
Probiotics and Fermented Foods
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