High-throughput identification of immunoreactive peptides and corresponding proteins from Anaplasma platys and Ehrlichia canis using peptide microarray chips
Our results suggest that a high-throughput strategy based on peptide microarrays is an effective approach for the rapid identification of immunoreactive peptides and the underlying immunogenic proteins. This study provides a foundation for developing novel diagnostic tools and vaccine candidates against <i>A. platys</i> and <i>E. canis</i>, including potential combined or multivalent formulations targeting both pathogens.
Authors
- Sreekumari Rajeev (ORCID: https://orcid.org/0000-0001-6600-9102)
- Alejandro Llanes (ORCID: https://orcid.org/0000-0002-6949-2782)
- Swetha Madesh (ORCID: https://orcid.org/0009-0004-3126-9114)
- Kalvis Brangulis
Institutions
- Latvian Biomedical Research and Study Centre (LV)
- Knoxville College (US)
- Secretaría Nacional de Ciencia, Tecnología e Innovación (PA)
- Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (PA)
- University of Tennessee at Knoxville (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/fcimb.2025.1671309
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00