Intestinal Ultrasound to Assess Disease Activity After Induction With Upadacitinib in Acute Severe Ulcerative Colitis

Intestinal ultrasound is a noninvasive, cost-effective tool to assess disease activity in ulcerative colitis (UC). Although upadacitinib, a selective Janus kinase 1 inhibitor, has demonstrated efficacy for induction therapy in patients with moderately to severely active UC, data in acute severe UC remain limited. We report on the use of intestinal ultrasound to assess treatment response after induction with upadacitinib in 3 patients hospitalized with acute severe UC.

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Publication Details

Journal
ACG Case Reports Journal
Published
2026-01-01
DOI
https://doi.org/10.14309/crj.0000000000001945
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Intestinal Ultrasound to Assess Disease Activity After Induction With Upadacitinib in Acute Severe Ulcerative Colitis

Jordan D. Perchik, Kirk Russ, Mohamed Saleh Ismail, Elena Gibson et al.
ACG Case Reports Journal
Inflammatory Bowel Disease
article

Intestinal Ultrasound to Assess Disease Activity After Induction With Upadacitinib in Acute Severe Ulcerative Colitis

Jordan D. Perchik, Kirk Russ, Mohamed Saleh Ismail, Elena Gibson, Lindsey Shipley
article en

Abstract

Intestinal ultrasound is a noninvasive, cost-effective tool to assess disease activity in ulcerative colitis (UC). Although upadacitinib, a selective Janus kinase 1 inhibitor, has demonstrated efficacy for induction therapy in patients with moderately to severely active UC, data in acute severe UC remain limited. We report on the use of intestinal ultrasound to assess treatment response after induction with upadacitinib in 3 patients hospitalized with acute severe UC.

ACG Case Reports JournalVol. 13(1)
University of Alabama at Birmingham (US)
Good health and well-being
Openalex Percentile: Top 95%
Inflammatory Bowel Disease
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Intestinal Ultrasound to Assess Disease Activity After Induction With Upadacitinib in Acute Severe Ulcerative Colitis — Jordan D. Perchik, Kirk Russ, et al. · ACG Case Reports Journal (2026) | TGRS Research Map | TGRS