Optimizing Gentamicin Dosing in Pediatric Oncology Patients
While oncology status has a minimal effect on gentamicin PK, the high prevalence of augmented renal clearance underscores the need for individualized dosing guided by PK modeling and therapeutic drug monitoring to ensure efficacy and minimize toxicity.
Authors
- S Alsanea
- Abdulrahman M. Alwhaibi
- Abdullah Alsultan (ORCID: https://orcid.org/0000-0002-7013-8369)
- Manal Abouelkheir (ORCID: https://orcid.org/0000-0001-6331-4443)
- Majed Al-Jeraisy
- Mohammed M. Almutairi
Institutions
- American Pharmacists Association (US)
- King Saud Medical City (SA)
- King Saud University (SA)
- Institute for Clinical Pharmacodynamics (United States) (US)
- PharmacoGenetics (China) (CN)
- National Guard Health Affairs (SA)
- Misr International University (EG)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1097/inf.0000000000005047
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00