[ <sup>18</sup> F]RO948 Tau PET Imaging in Early and Late‐Onset Alzheimer's Disease: Regional Evolution and Correlations with Plasma Biomarkers
[<sup>18</sup>F]RO948 PET can capture tau deposition at early stages of AD, particularly in medial temporal regions when plasma p-Tau217 levels similarly elevated. As the disease progresses to the clinical dementia stage, tau accumulation extends into cortical regions, with distinct regional deposition patterns observed between EOAD and LOAD.
Authors
- Konstantinos Chiotis (ORCID: https://orcid.org/0000-0002-5679-0297)
- G. Antoni
- Mariola Zapater‐Fajarí (ORCID: https://orcid.org/0000-0003-2529-4220)
- Marco Bucci (ORCID: https://orcid.org/0000-0002-5206-8651)
- J. G. Eriksson
- Kaj Blennow
- Agneta Nordberg (ORCID: https://orcid.org/0000-0001-7345-5151)
- Anders Wall
- Kübra Tan (ORCID: https://orcid.org/0000-0002-9092-2118)
- Wiebke Traichel
- Ilaria Pola
- Andrea L. Benedet
- Henrik Zetterberg
- Nenad Bogdanovic
- Nicholas Ashton
Institutions
- Uppsala University (SE)
- Karolinska University Hospital (SE)
- Uppsala University Hospital (SE)
- University of Wisconsin–Madison (US)
- King's College London (GB)
- Sahlgrenska University Hospital (SE)
- Turku University Hospital (FI)
- Karolinska Institutet (SE)
- Centre for Mental Health (GB)
- Turku PET Centre (FI)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104754
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00