Pharmacological Management of Anxiety in End‐of‐Life Care: A Systematic Review of Benzodiazepines, Opioids, and Psilocybin
Benzodiazepine-opioid combinations and psilocybin show promise for anxiety relief in end-of-life patients. Nevertheless, limited high-quality evidence highlights an important research gap. Further robust clinical trials are needed to confirm these findings and guide clinical practice in palliative care.
Authors
- Daniel Pagnin (ORCID: https://orcid.org/0000-0002-5213-3935)
- Brunno Freitas da Costa
- Paula Hartmann
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade Federal Fluminense (BR)
- Instituto Federal do Rio de Janeiro (BR)
- Hospital Universitário Antônio Pedro (BR)
Publication Details
- Journal
- Human Psychopharmacology Clinical and Experimental
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1002/hup.70032
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior