Oral Acid Load Lowers Bacterial Burden and Elevates Urinary Proinflammatory Response in a Mouse Model of Urinary Tract Infection

Thus, increased urine acid excretion reduced UPEC burden in urine and decreased risk of pyelonephritis while enhancing the urinary excretion of proinflammatory cytokines.

Authors

Helle A. Prætorius (ORCID: https://orcid.org/0000-0002-0970-5061)
Laura V. Sparsoe
Aimi D. K. Hamilton
Johanna Hornhaver
Mads Vaarby Sorensen

Institutions

Aarhus University (DK)

Publication Details

Journal: Acta Physiologica
Published: 2026-01-06
DOI: https://doi.org/10.1111/apha.70149
Primary Topic: Urinary Tract Infections Management
Type: article
Field-Weighted Citation Impact: 0.00

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article

Oral Acid Load Lowers Bacterial Burden and Elevates Urinary Proinflammatory Response in a Mouse Model of Urinary Tract Infection

Helle A. Prætorius, Laura V. Sparsoe, Aimi D. K. Hamilton, Johanna Hornhaver et al.

Jan 6, 2026

Acta Physiologica

Urinary Tract Infections Management

article

Oral Acid Load Lowers Bacterial Burden and Elevates Urinary Proinflammatory Response in a Mouse Model of Urinary Tract Infection

Helle A. Prætorius, Laura V. Sparsoe, Aimi D. K. Hamilton, Johanna Hornhaver, Mads Vaarby Sorensen

January 6, 2026article en

Abstract

Thus, increased urine acid excretion reduced UPEC burden in urine and decreased risk of pyelonephritis while enhancing the urinary excretion of proinflammatory cytokines.

Acta PhysiologicaVol. 242(2)

Aarhus University (DK)

Openalex Percentile: Top 97%

Urinary Tract Infections Management

DOI Open Access PDF OpenAlex

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Oral Acid Load Lowers Bacterial Burden and Elevates Urinary Proinflammatory Response in a Mouse Model of Urinary Tract Infection — Helle A. Prætorius, Laura V. Sparsoe, et al. · Acta Physiologica (2026) | TGRS Research Map | TGRS