Trigeminal Trophic Syndrome

Trigeminal Trophic Syndrome (TTS) is a rare, well-documented neurocutaneous condition characterized by the triad of paresthesia, analgesia, and ulcerations caused by self-manipulation, most commonly affecting the ala nasi. It typically arises following injury to the trigeminal nerve, either centrally or peripherally. We report the case of a 75-year-old woman who developed TTS following a cerebral stroke. Initially, her symptoms were misinterpreted as a psychiatric disorder, but the diagnosis of TTS was ultimately made based on the combination of prior trigeminal nerve injury and the classical symptom triad. This case highlights the diagnostic challenges of TTS and emphasizes the need to consider neurological etiologies in patients with atypical facial ulcerations.

Authors

Publication Details

Journal
Journal of Dermatology and Skin Science
Published
2025-12-12
DOI
https://doi.org/10.29245/2767-5092/2025/4.1206
Primary Topic
Trigeminal Neuralgia and Treatments
Type
article
Field-Weighted Citation Impact
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article

Trigeminal Trophic Syndrome

Caroline Thorup Ladegaard, Henrik Frank Lorentzen, Mathias Tiedemann Svendsen
Journal of Dermatology and Skin Science
Trigeminal Neuralgia and Treatments
article

Trigeminal Trophic Syndrome

Caroline Thorup Ladegaard, Henrik Frank Lorentzen, Mathias Tiedemann Svendsen
article en

Abstract

Trigeminal Trophic Syndrome (TTS) is a rare, well-documented neurocutaneous condition characterized by the triad of paresthesia, analgesia, and ulcerations caused by self-manipulation, most commonly affecting the ala nasi. It typically arises following injury to the trigeminal nerve, either centrally or peripherally. We report the case of a 75-year-old woman who developed TTS following a cerebral stroke. Initially, her symptoms were misinterpreted as a psychiatric disorder, but the diagnosis of TTS was ultimately made based on the combination of prior trigeminal nerve injury and the classical symptom triad. This case highlights the diagnostic challenges of TTS and emphasizes the need to consider neurological etiologies in patients with atypical facial ulcerations.

Journal of Dermatology and Skin ScienceVol. 7(4)
Good health and well-being
Openalex Percentile: Top 28%
Trigeminal Neuralgia and Treatments
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