Linking Energetic Inefficiency to Ventriculoarterial Uncoupling in Pulmonary Hypertension
TAPSE/sPAP remains a robust and clinically valuable surrogate of macroscopic RV-PA coupling. However, GWW offers complementary information by quantifying myocardial inefficiency related to paradoxical and postsystolic deformation, capturing energetic consequences of afterload mismatch that may not be reflected by displacement-based indices alone. Integrating energetic and mechanical markers may enable a more granular assessment of RV performance, particularly in intermediate-risk PH, and warrants evaluation in larger multicenter studies.
Authors
- Raluca Jumatate (ORCID: https://orcid.org/0000-0002-6361-4582)
- Annika Ingvarsson (ORCID: https://orcid.org/0000-0003-1968-8880)
- A Kovacs
- Ashwin Venkateshvaran (ORCID: https://orcid.org/0000-0002-0676-0604)
- Thomas Lindow (ORCID: https://orcid.org/0000-0002-2943-0034)
- Per Lindqvist
- Anna Werther Evaldsson
Institutions
- Semmelweis University (HU)
- Lund University (SE)
- Skåne University Hospital (SE)
- Centralsjukhuset Kristianstad (SE)
- Alstom (Sweden) (SE)
- Växjö Kommun (SE)
- Umeå University (SE)
Publication Details
- Journal
- Echocardiography
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1111/echo.70389
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00