Chromatin accessibility in MSC chondrogenesis, adult hip cartilage chondrocytes and osteoarthritis
This study illustrates the establishment of the chondrocyte chromatin landscape and identifies enhancer regions correlated with the cartilage transcriptome and associated with variants linked with cartilage disease OA.
Authors
- K. Cheung
- David J. Deehan (ORCID: https://orcid.org/0000-0001-5780-8818)
- Louise N. Reynard (ORCID: https://orcid.org/0000-0002-6613-1797)
- Jamie Soul (ORCID: https://orcid.org/0000-0003-2255-6459)
- Andreas Panagiotopoulos (ORCID: https://orcid.org/0000-0001-5212-7845)
- Julia Falk
- Matt J. Barter (ORCID: https://orcid.org/0000-0002-9158-8246)
- David Young (ORCID: https://orcid.org/0000-0002-4693-0663)
- Karina Putri
- Adam J. Farrier
Institutions
- Diponegoro University (ID)
- Roslin Institute (GB)
- University of Liverpool (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Freeman Hospital (GB)
- University of Indonesia (ID)
- Fios Genomics (United Kingdom) (GB)
- Newcastle University (GB)
Publication Details
- Journal
- Osteoarthritis and Cartilage
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1016/j.joca.2025.12.015
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00