Suxiao Jiuxin Pill Promotes Post-Myocardial Infarction Cardiac Repair by Enhancing Regulatory T Cell Function via the ST2L Signaling Pathway
This study elucidates the cardioprotective effects of SJP, which are mediated through the expansion of the Treg population and enhancement of their immunosuppressive function via activation of the ST2L/Foxp3 signaling pathway, with senkyunolide I and levistolide A identified as primary drivers behind the enhanced Treg function.
Authors
- Lusha Zhang
- Miaoxiu Li
- Hong Wang (ORCID: https://orcid.org/0000-0002-6192-3082)
- Tianyu Wang (ORCID: https://orcid.org/0000-0003-4169-8268)
- Qi Yu (ORCID: https://orcid.org/0000-0003-4528-4417)
- Ting Liu
- Ying Guo
- Shaoxia Wang
- Yuming Fan
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Xi'an Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/jir.s557620
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00