THE IMPACT OF DIABETES ON OCULAR HEALTH: MECHANISMS, COMPLICATIONS, AND MANAGEMENT

Background: Diabetes mellitus is a significant global health issue with profound impacts on ocular health, often leading to visual impairment and blindness. This study examines the prevalence, severity, and spectrum of ocular complications in individuals with diabetes, focusing on underlying mechanisms such as microvascular dysfunction, oxidative stress, and inflammation. Methods: A narrative research design was employed, analyzing retrospective clinical and ophthalmic data from 200 adult patients with type 1 and type 2 diabetes. Inclusion criteria required a confirmed diabetes diagnosis and comprehensive ophthalmic evaluation. Data on demographic characteristics, diabetes duration, glycemic control, and ocular findings were collected. Ocular complications were assessed using standardized criteria, and associations between systemic factors and ocular outcomes were analyzed using descriptive and comparative methods. Results: The study found a high burden of ocular complications, with diabetic retinopathy being the most prevalent (52.0%), followed by cataract (44.0%) and diabetic macular edema (23.0%). Longer diabetes duration and poor glycemic control were strongly associated with increased ocular involvement. Among participants with retinopathy, moderate non-proliferative disease was most common (42.3%), but advanced stages were present in 21.2% of cases. Only 24.0% of participants had no detectable ocular complications. Conclusion: Diabetes significantly impacts ocular health, with a high prevalence of vision-threatening complications linked to disease duration and metabolic control. These findings underscore the importance of early screening, strict glycemic management, and integrated ophthalmic care to prevent vision loss in diabetic patients.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-05
DOI
https://doi.org/10.5281/zenodo.18151691
Primary Topic
Retinal Diseases and Treatments
Type
article
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article

THE IMPACT OF DIABETES ON OCULAR HEALTH: MECHANISMS, COMPLICATIONS, AND MANAGEMENT

2Rana Mohammed Ahmed *1Harith Muhamed Ali Abd. Khalek
Zenodo (CERN European Organization for Nuclear Research)
Retinal Diseases and Treatments
article

THE IMPACT OF DIABETES ON OCULAR HEALTH: MECHANISMS, COMPLICATIONS, AND MANAGEMENT

2Rana Mohammed Ahmed *1Harith Muhamed Ali Abd. Khalek
article en

Abstract

Background: Diabetes mellitus is a significant global health issue with profound impacts on ocular health, often leading to visual impairment and blindness. This study examines the prevalence, severity, and spectrum of ocular complications in individuals with diabetes, focusing on underlying mechanisms such as microvascular dysfunction, oxidative stress, and inflammation. Methods: A narrative research design was employed, analyzing retrospective clinical and ophthalmic data from 200 adult patients with type 1 and type 2 diabetes. Inclusion criteria required a confirmed diabetes diagnosis and comprehensive ophthalmic evaluation. Data on demographic characteristics, diabetes duration, glycemic control, and ocular findings were collected. Ocular complications were assessed using standardized criteria, and associations between systemic factors and ocular outcomes were analyzed using descriptive and comparative methods. Results: The study found a high burden of ocular complications, with diabetic retinopathy being the most prevalent (52.0%), followed by cataract (44.0%) and diabetic macular edema (23.0%). Longer diabetes duration and poor glycemic control were strongly associated with increased ocular involvement. Among participants with retinopathy, moderate non-proliferative disease was most common (42.3%), but advanced stages were present in 21.2% of cases. Only 24.0% of participants had no detectable ocular complications. Conclusion: Diabetes significantly impacts ocular health, with a high prevalence of vision-threatening complications linked to disease duration and metabolic control. These findings underscore the importance of early screening, strict glycemic management, and integrated ophthalmic care to prevent vision loss in diabetic patients.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 95%
Retinal Diseases and Treatments
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THE IMPACT OF DIABETES ON OCULAR HEALTH: MECHANISMS, COMPLICATIONS, AND MANAGEMENT — 2Rana Mohammed Ahmed *1Harith Muhamed Ali Abd. Khalek · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS