Comparative Study Between Ultrasound Guided Transversus Thoracic Muscle Plane-Pectoral Nerve Block And Thoracic Paravertebral Block for Postoperative Analgesia After Modified Radical Mastectomy

Background: The incidence of breast cancer, the most frequent cancer among women, has been on the rise recently. Breast cancer treatment often involves surgery, with the gold standard invasive procedure being a modified radical mastectomy. Aim: The purpose of this research is to evaluate and contrast two approaches to pain management after a modified radical mastectomy procedure: a block to the pectoral nerve that is guided by ultrasonography and a block to the paravertebral space in the chest. The parameters of this comparison are the time it takes for the block to begin, the length of time it lasts, and the time it takes for the patient to request their first analgesic. Subjects and methods: The 106 participants in this randomized controlled experiment took place between August 2023 and August 2025 at Al-Azhar University Hospitals in Cairo, Egypt. Results: Both the 6-and 12-hour VAS scores were considerably lower in group A compared to group B (P=0.012 and 0.026, respectively). Group-A experienced a substantially longer delay in time to first request of rescue analgesia compared to group-B (P-value<0.001). Group-B had a considerably higher total morphine consumption (P-value<0.001) compared to group-A. Conclusion: According to patient satisfaction, complication rates, and intraoperative analgesic requirements, TTP-PECS appears to be a safer and more effective option for breast surgery patients seeking postoperative pain treatment.