Methylation and Expression Analysis of POU4F2, HOXA9, RBM46, and TSGA10 Genes in Bladder Cancer Using Methyl-Sensitive Restriction Enzyme PCR (MSRE-PCR)
The results indicate that these methylation and expression profiles can be used as non-invasive biomarkers for the early diagnosis of bladder cancer. The use of these methods provides both greater sensitivity and accuracy than traditional methods and can pave the way for the development of more effective screening tests.
Authors
- Mehrdad Noruzinia (ORCID: https://orcid.org/0000-0002-1325-3758)
- Mohammad Hossein Modarressi (ORCID: https://orcid.org/0000-0003-2763-1964)
- Shadi Mahdipour
Institutions
- Tarbiat Modares University (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/cmar.s557943
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00