Effectiveness and Safety of Eculizumab in Highly Active AChR+gMG and Its Therapeutic Response in Different Subtypes of gMG
Our study confirmed the safety and effectiveness of eculizumab in highly active gMG patients with reducing steroid dose. TAMG and MC may be suitable indications for treatment with eculizumab. All the muscle groups achieved improvements, especially for the extraocular muscles.
Authors
- Benqiao Wang
- Yong Liang (ORCID: https://orcid.org/0000-0003-3679-3084)
- Ruixia Zhu
- Tianying Ma
- Yanan Liu
- Yan Gao
- Ying Zhu
- Xue Wang
Institutions
- Dalian Medical University (CN)
- Harefield Hospital (GB)
- Second Affiliated Hospital of Dalian Medical University (CN)
- Liaoning Provincial People's Hospital (CN)
- First Hospital of China Medical University (CN)
- Anshan Hospital (CN)
- China Medical University (CN)
Publication Details
- Journal
- ImmunoTargets and Therapy
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/itt.s559497
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Liaoning Province