The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis

This meta-analysis suggests that EPOAP is associated with a reduced risk of reinfection following two-stage exchange arthroplasty for hip arthroplasty, while further research is warranted for knee cases. This approach may improve patient outcomes and help optimize post-operative antibiotic management.

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Publication Details

Journal
BMC Musculoskeletal Disorders
Published
2026-01-08
DOI
https://doi.org/10.1186/s12891-025-09410-4
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis

Allen Herng Shouh Hsu, Cheng-Ta Wu, Kuo Feng-Chih, Po-Chun Lin et al.
BMC Musculoskeletal Disorders
Orthopedic Infections and Treatments
article

The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis

Allen Herng Shouh Hsu, Cheng-Ta Wu, Kuo Feng-Chih, Po-Chun Lin, Chih-Wei Hsu, Pei-En Kao
article en

Abstract

This meta-analysis suggests that EPOAP is associated with a reduced risk of reinfection following two-stage exchange arthroplasty for hip arthroplasty, while further research is warranted for knee cases. This approach may improve patient outcomes and help optimize post-operative antibiotic management.

BMC Musculoskeletal DisordersVol. 27(1)
Chang Gung University (TW), Kaohsiung Chang Gung Memorial Hospital (TW), Cheng Shiu University (TW)
Good health and well-being
Openalex Percentile: Top 96%
Orthopedic Infections and Treatments
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