The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis
This meta-analysis suggests that EPOAP is associated with a reduced risk of reinfection following two-stage exchange arthroplasty for hip arthroplasty, while further research is warranted for knee cases. This approach may improve patient outcomes and help optimize post-operative antibiotic management.
Authors
- Allen Herng Shouh Hsu (ORCID: https://orcid.org/0000-0002-2378-1810)
- Cheng-Ta Wu
- Kuo Feng-Chih
- Po-Chun Lin
- Chih-Wei Hsu
- Pei-En Kao
Institutions
- Chang Gung University (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Cheng Shiu University (TW)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1186/s12891-025-09410-4
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00