Leveraging Genetic Instrumental Variables and Sequencing Analysis to Identify a Prognostic Signature Based on Epithelial Cell Markers in Lung Adenocarcinoma
The study developed a novel signature based on genes dynamically expressed during malignant AT2 cell dedifferentiation, capable of predicting the prognosis of LUAD patients, and offered four accurate prognostic biomarkers (ADM, MARK4, PARVA, and RPS6KA1).
Authors
- Ziqing Han (ORCID: https://orcid.org/0000-0001-7149-3162)
- Xinjing Lou (ORCID: https://orcid.org/0000-0002-1104-5728)
- Linyu Wu (ORCID: https://orcid.org/0000-0001-7695-0385)
- Jinxuan Ye
- Chen Gao
- Jiaye Lao
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1111/1759-7714.70244
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Westlake University
- Zhejiang Chinese Medical University
- Medical Research Council
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province