Context matters: Causality and global epidemiology of proton pump inhibitor safety
Proton pump inhibitors revolutionized acid-related disorder therapy, yet widespread overuse has raised concerns about long-term safety. A recent study in PLOS Medicine presents new evidence assessing whether links between their prolonged use and upper gastrointestinal cancer are causal.
Authors
- Gilaad G. Kaplan (ORCID: https://orcid.org/0000-0003-2719-0556)
- Shinji Okabayashi (ORCID: https://orcid.org/0000-0003-2683-9018)
Institutions
- University of Calgary (CA)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1371/journal.pmed.1004862
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00