Green synthesis of naphthyridines employing multicomponent and their antioxidant properties using

In this research work has effectively synthesized naphthyridines, which are categorized within a novel classification of fused heterocyclic compounds, by employing a multicomponent reaction with remarkable efficiency. The methodology incorporated 1-naphthol, 2-arylidenemalononitrile, activated acetylenic reagents, and imine derivatives of alkyl bromides in an aqueous medium at ambient temperature, with Cu@Fe3O4/SiO2 functioning as a recyclable catalyst. This scholarly investigation not only explores the antioxidant properties of naphthyridines but also builds upon prior research conducted in this domain. The synthesis of naphthyridines demonstrated numerous advantageous characteristics, including expedited reaction times, enhanced yields of the final product, and straightforward extraction of both the catalyst and product from the reaction mixture.

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Publication Details

Published
2025-12-30
DOI
https://doi.org/10.82361/iranjoc.2025.1230048
Primary Topic
Multicomponent Synthesis of Heterocycles
Type
article
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article

Green synthesis of naphthyridines employing multicomponent and their antioxidant properties using

Islamic Azad University
Multicomponent Synthesis of Heterocycles
article

Green synthesis of naphthyridines employing multicomponent and their antioxidant properties using

Islamic Azad University
article en

Abstract

In this research work has effectively synthesized naphthyridines, which are categorized within a novel classification of fused heterocyclic compounds, by employing a multicomponent reaction with remarkable efficiency. The methodology incorporated 1-naphthol, 2-arylidenemalononitrile, activated acetylenic reagents, and imine derivatives of alkyl bromides in an aqueous medium at ambient temperature, with Cu@Fe3O4/SiO2 functioning as a recyclable catalyst. This scholarly investigation not only explores the antioxidant properties of naphthyridines but also builds upon prior research conducted in this domain. The synthesis of naphthyridines demonstrated numerous advantageous characteristics, including expedited reaction times, enhanced yields of the final product, and straightforward extraction of both the catalyst and product from the reaction mixture.

Openalex Percentile: Top 32%
Multicomponent Synthesis of Heterocycles
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