Moderate to severe Chronic Hand Eczema in clinical practice: etiological subtypes, clinical signs and symptoms, and comorbidities—results from the RWEAL study

In conclusion, patients with moderate to severe CHE present with multiple etiological subtypes and a range of signs and symptoms. Many patients had no atopic condition besides CHE, and no history of atopic dermatitis, indicating that CHE is not simply atopic dermatitis of the hands.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2026-01-06
DOI
https://doi.org/10.1080/09546634.2025.2603121
Primary Topic
Contact Dermatitis and Allergies
Type
article
Field-Weighted Citation Impact
0.00
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article

Moderate to severe Chronic Hand Eczema in clinical practice: etiological subtypes, clinical signs and symptoms, and comorbidities—results from the RWEAL study

A M Gimenez-Arnau, Lysel Brignoli, Eydna Didriksen Apol, Anthony Bewley et al.
Journal of Dermatological Treatment
Contact Dermatitis and Allergies
article

Moderate to severe Chronic Hand Eczema in clinical practice: etiological subtypes, clinical signs and symptoms, and comorbidities—results from the RWEAL study

A M Gimenez-Arnau, Lysel Brignoli, Eydna Didriksen Apol, Anthony Bewley, Douglas Maslin, Christian Apfelbacher, Sonja Molin, Crepy Marie-Noëlle, Alexanne Morillo, Maria Concetta Fargnoli
article en

Abstract

In conclusion, patients with moderate to severe CHE present with multiple etiological subtypes and a range of signs and symptoms. Many patients had no atopic condition besides CHE, and no history of atopic dermatitis, indicating that CHE is not simply atopic dermatitis of the hands.

Journal of Dermatological TreatmentVol. 37(1)
Oracle (United States) (US), Universitat Pompeu Fabra (ES), Queen's University (CA), Leo Pharma (Australia) (AU), Barts Health NHS Trust (GB), Hotel Dieu Hospital (CA), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR), San Gallicano Hospital (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Charité - Universitätsmedizin Berlin (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Openalex Percentile: Top 96%
Contact Dermatitis and Allergies
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Moderate to severe Chronic Hand Eczema in clinical practice: etiological subtypes, clinical signs and symptoms, and comorbidities—results from the RWEAL study — A M Gimenez-Arnau, Lysel Brignoli, et al. · Journal of Dermatological Treatment (2026) | TGRS Research Map | TGRS