The Vascular Density/Angiogenesis Marker CD31/PECAM1 does not Correlate with Overall Survival in Neuroendocrine Tumors
NEN tumors are highly vascularized and consistently positive for CD31. Despite reports that CD31/PACAM1 is important to cell adhesion and tumor phenotype, there was no identifiable measurable impact of high CD31 levels on NEN. Nor was there a prognostic clinical value for CD31 staining quantification.
Authors
- Mary A. Maluccio
- Nicholas J. Skill (ORCID: https://orcid.org/0000-0003-0965-3836)
- Kenneth Avanzino
- Yvette Bren-Mattison
- Ramcharan Thiagarajan
- J. Philip Boudreaux
Institutions
- Louisiana State University Health Sciences Center New Orleans (US)
Publication Details
- Journal
- Journal of Gastrointestinal Cancer
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1007/s12029-025-01381-y
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00