Decoding neurotransmitter and genetic contributions to abnormal neuronal signal variability in Anti‑N‑Methyl‑D‑Aspartate receptor encephalitis: Implications for targeted therapies

This study identifies a transcriptional signature that is spatially associated with CV<sub>BOLD</sub>/FC abnormalities and neurotransmitter distributions in anti-NMDAR encephalitis, thereby generating hypotheses about molecular targets that may be relevant for future mechanistic studies and precision medicine.

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Publication Details

Journal
Brain Research Bulletin
Published
2026-01-01
DOI
https://doi.org/10.1016/j.brainresbull.2026.111717
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Decoding neurotransmitter and genetic contributions to abnormal neuronal signal variability in Anti‑N‑Methyl‑D‑Aspartate receptor encephalitis: Implications for targeted therapies

Rong Guo, Rui Qian, J. Zhang, Wei Wang et al.
Brain Research Bulletin
Autoimmune Neurological Disorders and Treatments
article

Decoding neurotransmitter and genetic contributions to abnormal neuronal signal variability in Anti‑N‑Methyl‑D‑Aspartate receptor encephalitis: Implications for targeted therapies

Rong Guo, Rui Qian, J. Zhang, Wei Wang, Qing Li, Si Xu, Yang Ji, Yuanyuan Guo, Yanghua Tian, Jiayun Wu, Ling Wei, Meidan Zu, Wenjia Wang, Wentao Dai, Wei Li
article en

Abstract

This study identifies a transcriptional signature that is spatially associated with CV<sub>BOLD</sub>/FC abnormalities and neurotransmitter distributions in anti-NMDAR encephalitis, thereby generating hypotheses about molecular targets that may be relevant for future mechanistic studies and precision medicine.

Brain Research BulletinVol. 234
Kunming University of Science and Technology (CN), Anhui Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN), Second Affiliated Hospital of Anhui Medical University (CN), Anhui Mental Health Center (CN)
Openalex Percentile: Top 96%
Autoimmune Neurological Disorders and Treatments
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Decoding neurotransmitter and genetic contributions to abnormal neuronal signal variability in Anti‑N‑Methyl‑D‑Aspartate receptor encephalitis: Implications for targeted therapies — Rong Guo, Rui Qian, et al. · Brain Research Bulletin (2026) | TGRS Research Map | TGRS