Elucidating the role of SHROOM4 in non-small cell lung cancer: expression patterns, clinical correlations, and potential functions

These results underscore the potential of <i>SHROOM4</i>, an anticancer role, as both a diagnostic and therapeutic target, particularly in LUSC. And <i>SHROOM4</i> may modulate NSCLC progression by affecting the TME in many ways. Further studies are essential to elucidate SHROOM4's role in lung cancer progression and to validate its clinical utility.