Association Between GLP-1 Receptor Agonists and Ischemic Optic Neuropathy: A Meta-analysis
GLP-1 RA use was associated with a modest increase in NAION risk but not overall ocular adverse events. Findings underscore the need for long-term postmarketing safety studies and should be interpreted against their well-established mortality and cardio-kidney-metabolic benefits.
Authors
- Nicole Felix (ORCID: https://orcid.org/0000-0001-8174-3866)
- Allêh Kauãn Santos Nogueira
- Nelson Rassi (ORCID: https://orcid.org/0009-0006-2145-3377)
- Filipe A. Moura (ORCID: https://orcid.org/0000-0001-8017-1675)
- T el Rassi
- Asad U. Khan (ORCID: https://orcid.org/0000-0001-9191-9423)
- Mauricio Maia
- Omar A. H. A. Alghaith
- Asad Iqbal
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Abdul Wali Khan University Mardan (PK)
- Yale University (US)
- Universidade Federal de Campina Grande (BR)
- VA Connecticut Healthcare System (US)
- Instituto de Gastroenterologia de Goiânia (BR)
- Instituto de Olhos de Goiânia (BR)
- University College London (GB)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Diabetes Care
- Published
- 2026-01-07
- DOI
- https://doi.org/10.2337/dc25-1238
- Citations
- 1
- Primary Topic
- Intraoperative Neuromonitoring and Anesthetic Effects
- Type
- article
- Field-Weighted Citation Impact
- 39.15