Atrial fibrillation signals associated with overactive bladder drugs across JADER and FAERS: disproportionality and time-to-onset analyses

These findings are hypothesis-generating, given the limitations of SRSs, such as underreporting, missing dates, and unknown exposure-and they reflect reporting patterns rather than causal risk. They outline strata and early treatment periods that may warrant clinical attention and help prioritize pharmacovigilance and targeted hypothesis-driven evaluation in routine OAB care.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-08
DOI
https://doi.org/10.3389/fphar.2025.1700587
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Atrial fibrillation signals associated with overactive bladder drugs across JADER and FAERS: disproportionality and time-to-onset analyses

Kiyoko Nagura, Taro Watanabe, Hidenori Sagara, Shiro Watanabe
Frontiers in Pharmacology
Atrial Fibrillation Management and Outcomes
article

Atrial fibrillation signals associated with overactive bladder drugs across JADER and FAERS: disproportionality and time-to-onset analyses

Kiyoko Nagura, Taro Watanabe, Hidenori Sagara, Shiro Watanabe
article en

Abstract

These findings are hypothesis-generating, given the limitations of SRSs, such as underreporting, missing dates, and unknown exposure-and they reflect reporting patterns rather than causal risk. They outline strata and early treatment periods that may warrant clinical attention and help prioritize pharmacovigilance and targeted hypothesis-driven evaluation in routine OAB care.

Frontiers in PharmacologyVol. 16
Yamaguchi Prefecture Central Hospital (JP), Sanyo-Onoda City University (JP)
Ministry of Science, ICT and Future Planning, U.S. Food and Drug Administration
Good health and well-being
Openalex Percentile: Top 96%
Atrial Fibrillation Management and Outcomes
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