Economic value of extended-window intravenous alteplase in posterior circulation stroke: a Markov analysis based on the EXPECTS trial
For patients with PCIS in the 4.5-24-h time window, intravenous alteplase is a highly cost-effective treatment option in China. This finding supports the broader implementation of extended-window thrombolysis for eligible PCIS patients, particularly in settings where access to endovascular thrombectomy or advanced perfusion imaging is limited.
Authors
- Yudong Ma
- Maolin Chen
- Yuhong Zeng
- Yake Lou
Institutions
- University of Electronic Science and Technology of China (CN)
- Capital Medical University (CN)
- Beijing Anzhen Hospital (CN)
- Air Force General Hospital PLA (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fphar.2025.1734165
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00