Rational design of DNA nanocarriers <i>via</i> sequence and length modulation of linker and lock domains: insights from coarse-grained simulations

Lock length and sequence composition jointly program the thermal stability, unlocking kinetics, and cargo-release behavior of DNA origami nanocarriers.

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Publication Details

Journal
Molecular Systems Design & Engineering
Published
2026-01-01
DOI
https://doi.org/10.1039/d5me00199d
Citations
2
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
Field-Weighted Citation Impact
44.47
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article

Rational design of DNA nanocarriers via sequence and length modulation of linker and lock domains: insights from coarse-grained simulations

Reza Soheilifard, Shima Danaeimoghaddam
2 citations
Molecular Systems Design & Engineering
Advanced biosensing and bioanalysis techniques
44.47
article

Rational design of DNA nanocarriers via sequence and length modulation of linker and lock domains: insights from coarse-grained simulations

Reza Soheilifard, Shima Danaeimoghaddam
article en
2 citations

Abstract

Lock length and sequence composition jointly program the thermal stability, unlocking kinetics, and cargo-release behavior of DNA origami nanocarriers.

Molecular Systems Design & EngineeringVol. 11(3)
Hakim Sabzevari University (IR)
Openalex Percentile: Top 1%
Advanced biosensing and bioanalysis techniques
44.47
DOISourceOpenAlex
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Rational design of DNA nanocarriers <i>via</i> sequence and length modulation of linker and lock domains: insights from coarse-grained simulations — Reza Soheilifard, Shima Danaeimoghaddam · Molecular Systems Design & Engineering (2026) | TGRS Research Map | TGRS