Reconsidering the Role of Blood Cultures in Community‐Acquired Pneumonia: A Case of Co‐Infection With <i>Streptococcus pneumoniae</i> and <i>Klebsiella variicola</i>

Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality. <i>Streptococcus pneumoniae</i> is the most common causative pathogen, with urinary antigen testing aiding the diagnosis thereof; however, blood culture yields are low, and guideline recommendations vary. We herein report a case of a 77-year-old man with pneumococcal pneumonia confirmed by urinary antigen testing whose blood cultures also revealed <i>Klebsiella variicola</i>. The detection of this co-infection would have been missed without blood cultures. Moreover, this combination of pathogens is first reported. This case underscores the importance of routine blood cultures in CAP diagnosis and supports the Japanese Respiratory Society's recommendation for their use in hospitalised patients.

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Publication Details

Journal
Respirology Case Reports
Published
2026-01-01
DOI
https://doi.org/10.1002/rcr2.70457
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Reconsidering the Role of Blood Cultures in Community‐Acquired Pneumonia: A Case of Co‐Infection With Streptococcus pneumoniae and Klebsiella variicola

Osamu Kanai, Takuma Imakita, Issei Oi, Naoki Fujimoto et al.
Respirology Case Reports
Pneumonia and Respiratory Infections
article

Reconsidering the Role of Blood Cultures in Community‐Acquired Pneumonia: A Case of Co‐Infection With Streptococcus pneumoniae and Klebsiella variicola

Osamu Kanai, Takuma Imakita, Issei Oi, Naoki Fujimoto, Kohei Fujita, Takanori Ito, Saiki Yoshimura, Kiminobu Tanizawa
article en

Abstract

Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality. <i>Streptococcus pneumoniae</i> is the most common causative pathogen, with urinary antigen testing aiding the diagnosis thereof; however, blood culture yields are low, and guideline recommendations vary. We herein report a case of a 77-year-old man with pneumococcal pneumonia confirmed by urinary antigen testing whose blood cultures also revealed <i>Klebsiella variicola</i>. The detection of this co-infection would have been missed without blood cultures. Moreover, this combination of pathogens is first reported. This case underscores the importance of routine blood cultures in CAP diagnosis and supports the Japanese Respiratory Society's recommendation for their use in hospitalised patients.

Respirology Case ReportsVol. 14(1)
Kyoto Medical Center (JP), Hikone Central Hospital (JP)
Good health and well-being
Openalex Percentile: Top 97%
Pneumonia and Respiratory Infections
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