The Bioinformatics Analysis of Publicly Available Datasets and Validation in a Mouse Model of Myocardial Infarction Through Coronary Artery Ligation
CMTM3 inhibits macrophage-related inflammation after MI by activating PPARα and inhibiting NF-κB phosphorylation. This study highlights the anti-inflammatory effect of CMTM3 in MI, and holds that CMTM3 can serve as a new target for improving cardiac remodeling after MI.
Authors
- Lin Zhong (ORCID: https://orcid.org/0000-0003-3698-784X)
- C Y Wang
- Mengyu Sun (ORCID: https://orcid.org/0000-0002-3545-3187)
- Hua Wang (ORCID: https://orcid.org/0000-0003-2606-9260)
- Jiahui Wang (ORCID: https://orcid.org/0000-0001-7685-1715)
- Xiaoning Ding
- Xiaoyan Jiang
- Fujun Liu
- Han Sun (ORCID: https://orcid.org/0009-0000-1471-6622)
- Wenlong Wang
Institutions
- Qingdao University (CN)
- Yuhuangding Hospital (CN)
- Shanghai Children's Medical Center (CN)
- Yantaishan Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/jir.s558274
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00