Effect of gentiopicroside on endogenous formaldehyde homocysteine–pathway related proteins in rats with non-alcoholic steatohepatitis
The GPS has therapeutic benefits in NASH rats as it improves liver weight, body weight, liver index levels, liver steatosis and liver function. The efficacy of GPS in ameliorating NASH in rats may be associated with the modulation of the endogenous FA-HCY pathway and attenuation of oxidative stress.
Authors
- Xiangqiong Li
- Xuan Ma
- Wenhui Chen (ORCID: https://orcid.org/0000-0001-8206-0733)
- A. Shi
- Yuhang Jiao
- Jie Chen (ORCID: https://orcid.org/0009-0002-8070-7323)
- Huiling Zuo
- Huanhuan Zhao
- Yahui Xiao
- Wei Zhao
Institutions
- Yunnan University (CN)
- First People's Hospital of Chongqing (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-06
- DOI
- https://doi.org/10.3389/fphar.2025.1700101
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00