Nonlinear associations between serum vitamin mixtures and cardiovascular disease risk: insights from a national cross-sectional analysis

The vitamin mixture shows an overall protective effect associated with lower CVD risk; contributions are primarily driven by vitamins C, D, and E, with A and B6 contributing risk and B12 playing a minimal role, and there is exploratory evidence of a D × B6 interaction.

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Publication Details

Journal
European journal of medical research
Published
2026-01-08
DOI
https://doi.org/10.1186/s40001-025-03741-7
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Nonlinear associations between serum vitamin mixtures and cardiovascular disease risk: insights from a national cross-sectional analysis

J. Jillian Zhang, Menglin Tian, Fuding Guo, MengTing Wei et al.
European journal of medical research
Folate and B Vitamins Research
article

Nonlinear associations between serum vitamin mixtures and cardiovascular disease risk: insights from a national cross-sectional analysis

J. Jillian Zhang, Menglin Tian, Fuding Guo, MengTing Wei, Chaoliang Nian, Sen Yang, Wenyin Du, Qiang Xue, Qiwei Liao, Xiaohua Zhao, Wenzhang Kuang
article en

Abstract

The vitamin mixture shows an overall protective effect associated with lower CVD risk; contributions are primarily driven by vitamins C, D, and E, with A and B6 contributing risk and B12 playing a minimal role, and there is exploratory evidence of a D × B6 interaction.

European journal of medical researchVol. 31(1)
Yunnan University (CN), Kunming Medical University (CN), Second Affiliated Hospital of Kunming Medical College (CN), Yunnan Center for Disease Control And Prevention (CN), Baoshan University (CN), Yan'an Hospital Affiliated To Kunming Medical University (CN)
Good health and well-being
Openalex Percentile: Top 97%
Folate and B Vitamins Research
DOIOpen Access PDFOpenAlex
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Nonlinear associations between serum vitamin mixtures and cardiovascular disease risk: insights from a national cross-sectional analysis — J. Jillian Zhang, Menglin Tian, et al. · European journal of medical research (2026) | TGRS Research Map | TGRS