Bayesian-Based Pharmacokinetic Framework Integrated with Therapeutic Drug Monitoring for Assessing Adherence to Antiseizure Medications: A Clinical Trial Simulation Study
This study establishes a Bayesian-based PK approach to enhance the assessment of ASMs adherence. This approach facilitates a paradigm shift from population-based management to patient-specific adherence profiling, offering a practical methodology for the precise evaluation of medication-taking behaviors.
Authors
- Zheng Jiao (ORCID: https://orcid.org/0000-0001-7999-7162)
- Wei-Wei Lin
- Ziran Li (ORCID: https://orcid.org/0000-0003-3795-4302)
- Xiao-Qin Liu
- Fu-Qing Gu
- Jun-Jie Ding
- Juan Wang
Institutions
- Fujian Medical University (CN)
- University of California, San Francisco (US)
- Angkor Hospital for Children (KH)
- Shanghai Chest Hospital (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Medical Internet Research
- Published
- 2026-01-02
- DOI
- https://doi.org/10.2196/77917
- Primary Topic
- Medication Adherence and Compliance
- Type
- article
- Field-Weighted Citation Impact
- 0.00