Foods Fortified with Soybean or Palm Oil Show No Effect on Inflammation or Oxidized Low-Density Lipoprotein in Adults with Overweight or Obesity: a Secondary Analysis of a Randomized Placebo-Controlled Crossover Trial
Incorporating study foods containing 30 g oil/d of soybean or palm oil had no significant impact on inflammatory markers, suggesting that higher LA intake is not proinflammatory as is stated in popular media outlets. In addition, a two week washout period may be sufficient for dietary oil interventions in crossover study designs.This trial was registered at clinicaltrials.gov as NCT04975763.
Authors
- Rachel M. Cole
- Martha A. Belury (ORCID: https://orcid.org/0000-0002-6480-4281)
- Eric Colombo
- Austin Angelotti (ORCID: https://orcid.org/0000-0002-7329-5044)
- Cheng-Tse Yang
- Andy Ni
Institutions
- The Ohio State University Wexner Medical Center (US)
- The Ohio State University (US)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107635
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00