Simvastatin combined with antiviral therapy for hepatitis B cirrhosis with portal hypertension: A case report

For hepatitis B cirrhosis patients with portal hypertension who are intolerant to or have contraindications for carvedilol, simvastatin combined with antiviral therapy is a safe, effective alternative. It significantly reduces HVPG, improves liver stiffness, and causes no obvious adverse events.

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Publication Details

Journal
Medicine
Published
2026-01-02
DOI
https://doi.org/10.1097/md.0000000000046933
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Simvastatin combined with antiviral therapy for hepatitis B cirrhosis with portal hypertension: A case report

Wei Gou, Haodong Zhang, Xuefang Li, Yong Zhou et al.
Medicine
Liver Disease and Transplantation
article

Simvastatin combined with antiviral therapy for hepatitis B cirrhosis with portal hypertension: A case report

Wei Gou, Haodong Zhang, Xuefang Li, Yong Zhou, Zhensheng Liu, Hui Wang, Xiaolong Qi, Jinjin Li
article en

Abstract

For hepatitis B cirrhosis patients with portal hypertension who are intolerant to or have contraindications for carvedilol, simvastatin combined with antiviral therapy is a safe, effective alternative. It significantly reduces HVPG, improves liver stiffness, and causes no obvious adverse events.

MedicineVol. 105(1)
Zhongda Hospital Southeast University (CN), Qingdao Center of Resource Chemistry and New Materials (CN)
Good health and well-being
Openalex Percentile: Top 97%
Liver Disease and Transplantation
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