Bilateral orofacial clefts are associated with increased risk of psychiatric morbidity relative to unilateral clefts
This large nationwide register study showed, for the first time, that individuals with bilateral clefts demonstrated elevated risks of psychiatric disorders compared with unilateral clefts. This is of clinical relevance to professionals as well as information that needs to be conveyed to families of children with orofacial clefts.
Authors
- Matilda A. Frick (ORCID: https://orcid.org/0000-0002-1307-4928)
- Jonas Höijer
- Daniel Nowinski (ORCID: https://orcid.org/0000-0002-8371-9314)
- Karin K. Tillman (ORCID: https://orcid.org/0000-0002-9030-909X)
- Fotios C. Papadopoulos (ORCID: https://orcid.org/0000-0002-8692-3652)
- Kjell Olsson (ORCID: https://orcid.org/0000-0002-1008-2690)
- Lisa Ekselius (ORCID: https://orcid.org/0000-0002-5760-7730)
- Malin Hakelius
- Mia Ramklint
Institutions
- Uppsala University (SE)
- Uppsala University Hospital (SE)
- Stockholm University (SE)
- Department of Medical Sciences (RU)
Publication Details
- Journal
- Journal of Plastic Reconstructive & Aesthetic Surgery
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1016/j.bjps.2025.12.038
- Primary Topic
- Cleft Lip and Palate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00