Evolving landscapes in childhood asthma-gut microbiota research: A bibliometric analysis from 2000 to 2024
This study underscores a paradigm shift from descriptive microbial profiling to mechanistic exploration of microbiota-derived metabolites (e.g., SCFAs) and early-life interventions. Future priorities include elucidating causal pathways via longitudinal cohorts, developing microbiota-targeted therapies, and leveraging multi-omics integration. Despite limitations in database scope, this analysis highlights accelerating translation from basic research to clinical applications through global collaboration. Researchers should prioritize interdisciplinary studies to unravel the "microbiome-immune-development" triad and optimize personalized asthma management.
Authors
- HongMan Wang
- Yanxin Lu
- Yang Zhao
- Dan Lou
Institutions
- Sun Yat-sen University (CN)
- Zunyi Medical University (CN)
- Zhuhai People's Hospital (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
Publication Details
- Journal
- Medicine
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1097/md.0000000000046594
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00