Evolving landscapes in childhood asthma-gut microbiota research: A bibliometric analysis from 2000 to 2024

This study underscores a paradigm shift from descriptive microbial profiling to mechanistic exploration of microbiota-derived metabolites (e.g., SCFAs) and early-life interventions. Future priorities include elucidating causal pathways via longitudinal cohorts, developing microbiota-targeted therapies, and leveraging multi-omics integration. Despite limitations in database scope, this analysis highlights accelerating translation from basic research to clinical applications through global collaboration. Researchers should prioritize interdisciplinary studies to unravel the "microbiome-immune-development" triad and optimize personalized asthma management.

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Publication Details

Journal
Medicine
Published
2026-01-02
DOI
https://doi.org/10.1097/md.0000000000046594
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Evolving landscapes in childhood asthma-gut microbiota research: A bibliometric analysis from 2000 to 2024

HongMan Wang, Yanxin Lu, Yang Zhao, Dan Lou
Medicine
Gut microbiota and health
article

Evolving landscapes in childhood asthma-gut microbiota research: A bibliometric analysis from 2000 to 2024

HongMan Wang, Yanxin Lu, Yang Zhao, Dan Lou
article en

Abstract

This study underscores a paradigm shift from descriptive microbial profiling to mechanistic exploration of microbiota-derived metabolites (e.g., SCFAs) and early-life interventions. Future priorities include elucidating causal pathways via longitudinal cohorts, developing microbiota-targeted therapies, and leveraging multi-omics integration. Despite limitations in database scope, this analysis highlights accelerating translation from basic research to clinical applications through global collaboration. Researchers should prioritize interdisciplinary studies to unravel the "microbiome-immune-development" triad and optimize personalized asthma management.

MedicineVol. 105(1)
Sun Yat-sen University (CN), Zunyi Medical University (CN), Zhuhai People's Hospital (CN), Fifth Affiliated Hospital of Sun Yat-sen University (CN), First Affiliated Hospital of Henan University of Science and Technology (CN)
Openalex Percentile: Top 96%
Gut microbiota and health
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