A Novel Rat Model for Human Meibomian Gland Dysfunction and Ocular Rosacea
This model is a valuable tool for studying the pathophysiology of MGD in OR and evaluating new treatments. The transcriptomic and lipidomic similarities between rat model and human disease provide insights into shared molecular pathways and lipid composition, offering potential biomarkers for diagnosis and therapeutic targets.
Authors
- Francine Béhar‐Cohen (ORCID: https://orcid.org/0000-0001-8571-9513)
- Emmanuelle Gélizé
- X Morel
- Caroline Peltier (ORCID: https://orcid.org/0000-0002-7926-955X)
- C. Lheure (ORCID: https://orcid.org/0000-0002-9694-8386)
- Olivier Berdeaux (ORCID: https://orcid.org/0000-0003-3675-0324)
- Jean‐Louis Bourges (ORCID: https://orcid.org/0000-0002-7016-9819)
- Marine Crépin (ORCID: https://orcid.org/0009-0005-5746-7394)
- Linxin Zhu (ORCID: https://orcid.org/0000-0002-8235-0105)
- Daniela Rodrigues-Braz
- Min Zhao
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Sorbonne Université (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Centre de Recherche des Cordeliers (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Institut Agro Dijon (FR)
- Centre des Sciences du Goût et de l'Alimentation (FR)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1167/iovs.67.1.14
- Primary Topic
- Acne and Rosacea Treatments and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00