Analysis of molecular subtypes and prognostic signature of senescence-associated secretory phenotype in pancreatic cancer
Molecular subtyping and risk stratification based on SASP genes effectively predict PC prognosis and reveal heterogeneity in mutational burden, immune microenvironment, and therapeutic sensitivity. These computational findings deepen our understanding of potential role of SASP in PC and provide a theoretical foundation for personalized treatment strategies.
Authors
- Yuming Zhu (ORCID: https://orcid.org/0000-0002-4833-4240)
- Zhiyong Xiang
- Mingkun Jia
- Yuewen Kuang
Institutions
- Third People 's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-01-06
- DOI
- https://doi.org/10.7717/peerj.20476
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00