A case of necrotizing pneumonia leading to respiratory failure and tracheostomy

Necrotizing pneumonia is a severe lung infection characterized by pulmonary necrosis and high mortality rates of up to 50 %. It is typically caused by toxin-producing pathogens, such as <i>Staphylococcus aureus</i> and <i>Klebsiella pneumoniae</i>. Limited guidelines exist for its management, making its treatment challenging. Case report: We discuss a case of a 58-year-old Malay woman with no significant comorbidity but developed necrotizing pneumonia. The diagnosis was confirmed using computed tomography (CT) of the thorax. Treatment with carbapenem, oxazolidinone and corticosteroid led to significant recovery. Conclusion: To date, no specific anti-inflammatory treatments exist for severe necrotizing pneumonia. Since systemic inflammation and multi-organ failure drive mortality, management focuses on supportive care aimed at maintaining oxygenation and hemodynamic stability to improve outcomes in critically ill patients.

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Publication Details

Journal
IDCases
Published
2026-01-01
DOI
https://doi.org/10.1016/j.idcr.2025.e02480
Primary Topic
Nosocomial Infections in ICU
Type
article
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article

A case of necrotizing pneumonia leading to respiratory failure and tracheostomy

Tuan Sharifah Syuwaibah Tuan Zainal, Nurul Aifaa Mohd Azmi, Mazlan Mohd Zulfakar, Shao Keong Koeh
IDCases
Nosocomial Infections in ICU
article

A case of necrotizing pneumonia leading to respiratory failure and tracheostomy

Tuan Sharifah Syuwaibah Tuan Zainal, Nurul Aifaa Mohd Azmi, Mazlan Mohd Zulfakar, Shao Keong Koeh
article en

Abstract

Necrotizing pneumonia is a severe lung infection characterized by pulmonary necrosis and high mortality rates of up to 50 %. It is typically caused by toxin-producing pathogens, such as <i>Staphylococcus aureus</i> and <i>Klebsiella pneumoniae</i>. Limited guidelines exist for its management, making its treatment challenging. Case report: We discuss a case of a 58-year-old Malay woman with no significant comorbidity but developed necrotizing pneumonia. The diagnosis was confirmed using computed tomography (CT) of the thorax. Treatment with carbapenem, oxazolidinone and corticosteroid led to significant recovery. Conclusion: To date, no specific anti-inflammatory treatments exist for severe necrotizing pneumonia. Since systemic inflammation and multi-organ failure drive mortality, management focuses on supportive care aimed at maintaining oxygenation and hemodynamic stability to improve outcomes in critically ill patients.

IDCasesVol. 43
Hospital Universiti Sains Malaysia (MY)
Good health and well-being
Openalex Percentile: Top 96%
Nosocomial Infections in ICU
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