Novel Acrylamide Derivatives as Mitochondrial Permeability Transition Pore (mPTP) Inhibitors for Treating Neurodegenerative Diseases
Provided herein are novel acrylamide derivatives as mitochondrial permeability transition pore (mPTP) inhibitors, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, and processes for preparing such compounds.
Authors
- Anika R. Sabnis (ORCID: https://orcid.org/0009-0008-9940-6583)
- R. W. Sabnis
Institutions
- Mayo Clinic (US)
Publication Details
- Journal
- ACS Medicinal Chemistry Letters
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1021/acsmedchemlett.5c00778
- Primary Topic
- Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00