Identification of PANoptosis-Related Biomarkers in Hypertrophic Cardiomyopathy: Insights from Multi-Omics Analysis
This study provides the first systematic evidence linking PANoptosis to the molecular pathogenesis of HCM. PANoptosis contributes to HCM pathogenesis and immune remodeling, and the identified biomarkers demonstrate translational potential as diagnostic indicators and therapeutic targets. The integrated analysis highlights novel PANoptotic signaling axes that may guide future precision diagnosis and intervention strategies for HCM.
Authors
- Jinlong Zhong
- Qian Zhao (ORCID: https://orcid.org/0000-0002-9540-5726)
- G H Liu
- Shuguang Zhang
- Lin Shi (ORCID: https://orcid.org/0000-0002-5577-7437)
- Xia Han
- Zhihui Zhang (ORCID: https://orcid.org/0009-0003-3945-2872)
- Ruiqing Wu
Institutions
- Shanghai Public Security Bureau (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/jir.s555505
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00